Most likely to cause adenovirus hepatitis F41 – Health

“The European Union is closely following the situation, which is concerning” and countries “must share all possible information.” This is how the European Commissioner for Health Stella Kyriakides commented on the cases of hepatitis of unknown origin registered in Europe. “As of April 25, there have been nearly 40 cases in member states – continued the commissioner – so far cases have been recorded among children aged between one month and sixteen years, the possible origin is viral, but we need more information, we will ecdc publishes its first evaluation tomorrow. Invite countries to share all possible information

English language agency, ADENOVIRUS F41 The most likely reason
“Adenovirus is the most common pathogen detected in 75% of confirmed cases” of acute hepatitis in children in Britain, and in particular, “the strain of adenovirus called F41 appears to be the most likely cause.” This is confirmed by the UK Health Safety Agency (UKHSA) in a report, which maintains the hypothesis that this virus may be the origin of rare hepatitis of unknown origin that has occurred in several countries, including Italy. Scientists are studying whether there is a change in the genetic makeup of the virus that could more easily lead to hepatitis. In the agency’s report, updated until April 25 and released by the British media, it was emphasized that most children who contract adenovirus do not develop particularly severe symptoms. “Information collected through our investigations increasingly indicates that this increase in the sudden onset of hepatitis in children is associated with adenovirus infection,” said Mira Chand, director of clinical and emerging infections at Ukhsa. “However, we are meticulously investigating other possible causes.” Another possible explanation is that the precautionary measures imposed in the pandemic may have resulted in young children being exposed to the adenovirus for the first time later in life than would normally occur, resulting in a more robust immune response, in some cases. , against adenoviruses. Other hypotheses are still being studied as well, including the fact that a recent Covid infection could be a cause of liver problems along with the adenovirus. The UK’s Health Security Agency was the first, on April 6, to sound the alarm, reporting the first 60 suspected cases. It was immediately alerted by the European Centers for Disease Control and Prevention (ECDC) and the World Health Organization (WHO).

A case has been reported in Japan
The mysterious liver disease, which has infected children in a dozen countries around the world, has also reached Asia, where local authorities reported a case in Japan on April 21. According to The Guardian, the patient tested negative for adenovirus – a possible cause of acute hepatitis, which is being investigated around the world – and Covid-19. To date, 190 ambiguous cases of acute hepatitis in children have been reported, including 140 in Europe, mainly in the United Kingdom (110 cases). Additional cases were found in Israel and the United States. The UN health agency said cases were reported in children aged between one month and 16 years. One theory being studied by the UK’s Health Safety Agency is that reduced exposure to the common adenovirus – which usually causes stomach upsets and colds – during the coronavirus pandemic has led to more serious illness among children. UK officials have denied a possible link between the cases and the Covid-19 vaccine because none of the children with hepatitis have received the vaccination.

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