Covid, Omicron’s “show” that surprised science: “The positives were underestimated by up to 4 times. And many “sham” cases went undetected”

A surge in injuries – despite the heat – an omicron spread that “surprised everyone” and that results in a torrent of cases that don’t go into the chain even “three or even four times” compared to official data. It must be added to these cases that Massimo ClementeProfessor and Director of the Microbiology and Virology LaboratoryVita-Salute San Raffaele University in Milan, “sneaky” is defined by only lowering the volume and a positive that can last even for a short time. And you probably won’t notice if you don’t wipe. “Now we are all spectators of the Omicron 5 show which surprised everyone from the point of view of the intensity of the spread. I hope – as the world says – in the decline that occurred in other parts of the world.”

Professor, injuries are still many, summer does not stop the virus
Let’s start from a positive fact: Omicron 4 and 5, which support all of these conditions, can also cause an infection with few symptoms. In some countries, such as Portugal, the wave has been there and is now receding. And let’s remember that the virus “suffers” more than heat from ultraviolet radiation.

As for reducing cases. There are those who believe that the number of positives should be doubled, tripled, or even quadrupled. agree?
Yes, of course. Then there are the disingenuous cases that just don’t fit in with the stats. There are people who only have a low voice and their earplugs are positive. But there are also those who do not possess this curiosity, and the case goes unnoticed.

Then there is re-infection: with delta it was 2% and with omicron it exceeded 8%. In short, should herd immunity be lifted permanently?
I would say yes. What matters is the impossibility in the current situation to prevent this virus, unless specially designed vaccines against Omicron work. Immunity is currently compromised by Omicron, although vaccination saves us from hospitalization and death. The infection affects all upper airways and is therefore not a clinical concern. The extent of its spread will depend on the ability to mutate and this virus has a tremendous ability to reproduce. I don’t think it will last indefinitely, although it’s hard to say. We will have to live with this virus.

Omicron 5, in addition to the proliferation advantage over the Ba.2 and Ba.3 copies (which were already more infectious than Delta), has a difference, L452R, present in the Delta variant…
But it’s still an Omicron and is part of the evolutionary streak that started last November (in South Africa, ed.)

We are waiting for the bivalent vaccines, but it has been shown that they have half the Rna from the Wuhan strain and half from Omicron 1. But we know that those infected with Omicron 1 can get infected again with the latest versions.
It is clear that the immunity conferred by a bivalent vaccine is always better than that developed on the virus circulating in Wuhan. And in any case, we cannot believe that immunity exceeds 6 months, because even the natural immunity conferred by infection persists for a long time. This is a feature of these viruses and even with influenza this is the case. We repeat the vaccination every year.

So a new vaccination campaign. When should we start and what categories do we start with?
In September, vaccines that have already shown good efficacy in the tests carried out will be ready. So in September, October. Elderly people and comorbidities should be vaccinated immediately. Then it will be necessary to consider the extension.

And what about the children? And those who have already been vaccinated?
Yes, because we’ve seen that Omicron has the potential to infect even children under the age of ten. In view of the resumption of the study, it would be better if they were vaccinated.

Some say we need to prepare for a terrible October. What do you think, is it a possibility?
I wouldn’t venture to make predictions and I don’t know on what basis you make them.

However, this virus has demonstrated capabilities that other coronaviruses do not have
It has a far superior ability to injure than others. It forms highly duplicated, highly prevalent variants, which have given up pathogenicity as they infect the lower airways: with less pneumonitis to spread more. This thing hasn’t been seen with other coronaviruses: the first SARS epidemic, with 8,000 cases that would make us laugh today but at the time it worried us so much, it ended abruptly. This virus infected mainly health professionals, and poor Dr. Urbani (a microbiologist who recognized SARS and died in 2003) became infected at the French Hospital in Saigon.

At the beginning of the epidemic in Science, an article was published by some scientists who hypothesized, based on a prediction model based on four betacoronaviruses, that the epidemic after several waves in 2022 and stabilizing in 2023, will (possibly) end in 2024. In light of how much From the time we live are they right?
can be realistic. More likely, there is an ongoing waiting list for infection. Infection is one thing and the ability to cause serious illness is another. It’s no small fact, we already live with thousands of viruses.

So how do we get to 2024 unharmed or nearly unharmed?
This model predicts that waves are becoming less significant. Now we are all spectators of the Omicron 5 show which surprised everyone from the point of view of the intensity of the spread. I hope the decline that has occurred in other parts of the world will happen.

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