Severe cases of COVID-19 are on the rise in children who are unvaccinated. In the range From 5 to 11 years the effectiveness of an anti-Covid-19 vaccine It was lower than those in the licensing studies, with 29% protecting against infection and 41% against serious disease, and for the unvaccinated, the incidence of severe forms of the disease was twice that of those given the two doses. These are the results of one A study by the Higher Institute of Health and the Ministry of Health published by The Lancet.. The researchers studied data on more than 1 million children vaccinated with two doses, 134,000 in a single dose and 1.8 million unvaccinated.
Efficacy was estimated by comparing data from the Integrated Surveillance System for Covid-19 with those in the National Immunization Registry, considering all previously undiagnosed children aged 5-11 years who were followed between 17 January and 17 January. April 13, 2022, a period characterized by the dominance of the Omicron variant.
In the mentioned period, approximately 767,000 cases in the 5-11 year range were notified to the monitoring system. The rate was highest in the unvaccinated group (426.9 per 100,000 person-day), and lowest in the two-dose vaccinated group (234.5 per 100,000 person-day). Also in the mentioned period, there were 644 serious cases of Covid-19, all of whom were hospitalized. Of those, 15 were admitted to intensive care and two died, only among the unvaccinated. The incidence of severe disease doubled in the unvaccinated (0.6 per 100,000 person-day vs. 0.3). “The analysis indicates – as the authors emphasized in the article – a specific period in which the Omicron variant was dominant. Even moderate protection contributed significantly to reducing the effects of infection, especially the more serious ones, as demonstrated by the difference in infection from severe cases in the two groups.”